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AboutAboutSerotypesMechanism of ActionCAPiTA: Prevnar 13 Efficacy profileImmunogenicity profileSafety profilePatient profilesDosingDosingDosingPneumococcal diseasePneumococcal diseasePneumococcal diseasePneumococcal serotypesRisk factorsRecommendationsRecommendationsRecommendationsResourcesResourcesMaterialsVideos
Important Safety InformationProduct Monograph
TitlePREVNAR 20™ (Pneumococcal 20-valent Conjugate Vaccine [Diphtheria CRM197 Protein]) is indicated for active immunization of adults 18 years of age and older for the prevention of pneumonia and invasive pneumococcal disease (including sepsis, meningitis, bacteremic pneumonia, pleural empyema and bacteremia) caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F.1PREVNAR 20™Help prevent pneumococcal pneumonia and invasive pneumococcal disease (IPD) with one dose1* NACI recommendations on PREVNAR 202

Learn more about the NACI recommendations for use of PREVNAR 20 in adult patients

PREVNAR 20: Broad serotype coverage from a pneumococcal conjugate vaccine for adults3

Explore the serotype of Streptococcus pneumoniae included in PREVNAR 20

Incidence of IPD in Canada in 2021 (per 100,000 people)4

Learn more about the incidence of invasive pneumococcal disease

Important Safety Information PREVNAR 20

Indication and clinical use:

PREVNAR 20 is indicated for active immunization of adults 18 years of age and older for the prevention of pneumonia and invasive pneumococcal disease (including sepsis, meningitis, bacteremic pneumonia, pleural empyema and bacteremia) caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 8, 9V, 10A, 11A, 12F, 14, 15B, 18C, 19A, 19F, 22F, 23F, and 33F.1

Clinical efficacy for the prevention of pneumonia was studied with PREVNAR 13 for the shared serotypes, but not for additional serotypes 8, 10A, 11A, 12F, 15B, 22F, and 33F.

Relevant warnings and precautions:

  • Immunocompromised individuals may have a reduced antibody response to the vaccine.1

  • Safety and immunogenicity data on PREVNAR 20 are not available for individuals in certain immunocompromised groups (e.g., those with malignancy or nephrotic syndrome) and vaccination should be considered on an individual basis. Some safety and immunogenicity data are available in individuals with sickle cell disease, HIV infection, or hematopoietic stem cell transplant.1

  • The administration of PREVNAR 20 should be postponed in individuals with acute severe febrile illness.1

  • As with any intramuscular injection, PREVNAR 20 should be given with caution in individuals with thrombocytopenia or any coagulation disorder, or receiving anticoagulant therapy.1

  • May not protect all individuals from pneumococcal disease.1

  • Exercise caution when driving or operating a vehicle or potentially dangerous machinery.5

 

For more information:

Please consult the Product Monograph for important information relating to adverse reactions, drug interactions, and dosing information, which have not been discussed in this piece. The Product Monograph is also available on request by calling 1-800-463-6001.

PREVNAR 13

Indication:

PREVNAR 13 is indicated for active immunization of adults 18 years of age and older for the prevention of pneumonia and invasive pneumococcal disease (including sepsis, meningitis, bacteremic pneumonia, pleural empyema and bacteremia) caused by Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, and 23F.5

Relevant warnings and precautions:

  • Immunocompromised individuals may have a reduced antibody response to the vaccine.5

  • Safety and immunogenicity data on PREVNAR 13 are not available for individuals in certain immunocompromised groups (e.g., those with malignancy or nephrotic syndrome) and vaccination should be considered on an individual basis. Some safety and immunogenicity data are available in individuals with sickle cell disease, HIV infection, or hematopoietic stem cell transplant.5

  • The administration of PREVNAR 13 should be postponed in individuals with acute severe febrile illness.

  • As with any intramuscular injection, PREVNAR 13 should be given with caution in individuals with thrombocytopenia or any coagulation disorder, or receiving anticoagulant therapy.

  • May not protect all individuals from pneumococcal disease.5

  • Exercise caution when driving or operating a vehicle or potentially dangerous machinery.5

 

For more information:

Please consult the Product Monograph for important information relating to adverse reactions, drug interactions, and dosing information, which have not been discussed in this piece. The Product Monograph is also available on request by calling 1-800-463-6001.

NACI: National Advisory Committee on Immunization  
* Please refer to the Product Monograph for complete dosing information.  
† Comparative clinical significance is unknown.
References:PREVNAR 20 Product Monograph. Pfizer Canada ULC.An Advisory Committee Statement (ACS) National Advisory Committee on Immunization (NACI) Public health level recommendations on the use of pneumococcal vaccines in adults, including the use of 15-valent and 20-valent conjugate vaccines. February 2023. Accessed on June 17, 2024.Pfizer Inc. Data on file. 2024.Public Health Agency of Canada. Invasive pneumococcal disease surveillance in Canada, 2021-2022. May 2024. Accessed on June 17, 2024.PREVNAR 13 Product Monograph. Pfizer Canada ULC.
PP-PNR-CAN-0140. November 2024

To report an adverse event, please call 1-866-723-7111

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